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2015 Published Articles

1. Zhu J, Chen C, Yang B, Guo Y, Ai H, Ren J, et al. A systems genetics study of swine illustrates mechanisms underlying human phenotypic traits. BMC Genomics. 2015;16(1):88. doi: 10.1186/s12864-015-1240-y.
2. Zhang Z, Hao K. SAAS-CNV: A Joint Segmentation Approach on Aggregated and Allele Specific Signals for the Identification of Somatic Copy Number Alterations with Next-Generation Sequencing Data. PLoS computational biology. 2015;11(11):e1004618-e. doi: 10.1371/journal.pcbi.1004618. PubMed PMID: 26583378.
3. Zhang G, Smith SG, Zhou M-M. Discovery of Chemical Inhibitors of Human Bromodomains. Chemical Reviews. 2015;115(21):11625-68. doi: 10.1021/acs.chemrev.5b00205.
4. Yoo S, Takikawa S, Geraghty P, Argmann C, Campbell J, Lin L, et al. Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD. PLOS Genetics. 2015;11(1):e1004898. doi: 10.1371/journal.pgen.1004898.
5. Yang Y, Sebra R, Pullman BS, Qiao W, Peter I, Desnick RJ, et al. Quantitative and multiplexed DNA methylation analysis using long-read single-molecule real-time bisulfite sequencing (SMRT-BS). BMC genomics. 2015;16(1):350-. doi: 10.1186/s12864-015-1572-7. PubMed PMID: 25943404.
6. Yang J, Huang T, Petralia F, Long Q, Zhang B, Argmann C, et al. Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases. Scientific Reports. 2015;5:15145. doi: 10.1038/srep15145
https://www.nature.com/articles/srep15145 - supplementary-information.
7. Xu K, Schadt EE, Pollard KS, Roussos P, Dudley JT. Genomic and Network Patterns of Schizophrenia Genetic Variation in Human Evolutionary Accelerated Regions. Molecular Biology and Evolution. 2015;32(5):1148-60. doi: 10.1093/molbev/msv031.
8. Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLOS Genetics. 2015;11(10):e1005378. doi: 10.1371/journal.pgen.1005378.
9. Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, et al. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications. 2015;6:5897. doi: 10.1038/ncomms6897
https://www.nature.com/articles/ncomms6897 - supplementary-information.
10. Webb BD, Wheeler PG, Hagen JJ, Cohen N, Linderman MD, Diaz GA, et al. Novel, compound heterozygous, single-nucleotide variants in MARS2 associated with developmental delay, poor growth, and sensorineural hearing loss. Human mutation. 2015;36(6):587-92. Epub 2015/04/08. doi: 10.1002/humu.22781. PubMed PMID: 25754315.
11. Webb BD, Wheeler PG, Hagen JJ, Cohen N, Linderman MD, Diaz GA, et al. Novel, Compound Heterozygous, Single Nucleotide Variants in MARS2 Associated with Developmental Delay, Poor Growth, and Sensorineural Hearing Loss. Human mutation. 2015;36(6):587-92. doi: 10.1002/humu.22781. PubMed PMID: PMC4439286.
12. Wang Z, Rajaraman P, Melin BS, Chung CC, Zhang W, McKean-Cowdin R, et al. Further Confirmation of Germline Glioma Risk Variant rs78378222 in TP53 and Its Implication in Tumor Tissues via Integrative Analysis of TCGA Data. Human mutation. 2015;36(7):684-8. Epub 2015/05/18. doi: 10.1002/humu.22799. PubMed PMID: 25907361.
13. Wang M, Zhao Y, Zhang B. Efficient Test and Visualization of Multi-Set Intersections. Scientific Reports. 2015;5:16923. doi: 10.1038/srep16923
https://www.nature.com/articles/srep16923 - supplementary-information.
14. Wang L, Gong Y, Chippada-Venkata U, Heck MM, Retz M, Nawroth R, et al. A robust blood gene expression-based prognostic model for castration-resistant prostate cancer. BMC Medicine. 2015;13:201. doi: 10.1186/s12916-015-0442-0. PubMed PMID: PMC4546313.
15. Wang J, Liao J, Zhang J, Cheng W-Y, Hakenberg J, Ma M, et al. ClinLabGeneticist: a tool for clinical management of genetic variants from whole exome sequencing in clinical genetic laboratories. Genome Medicine. 2015;7(1):77. doi: 10.1186/s13073-015-0207-6. PubMed PMID: PMC4558641.
16. Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, et al. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American journal of human genetics. 2015;97(4):576-92. Epub 2015/10/01. doi: 10.1016/j.ajhg.2015.09.001. PubMed PMID: 26430803.
17. Vardabasso C, Gaspar-Maia A, Hasson D, Pünzeler S, Valle-Garcia D, Straub T, et al. Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma. Molecular cell. 2015;59(1):75-88. Epub 2015/06/04. doi: 10.1016/j.molcel.2015.05.009. PubMed PMID: 26051178.
18. Udler MS, Nadkarni GN, Belbin G, Lotay V, Wyatt C, Gottesman O, et al. Effect of Genetic African Ancestry on eGFR and Kidney Disease. Journal of the American Society of Nephrology : JASN. 2015;26(7):1682-92. doi: 10.1681/ASN.2014050474. PubMed PMID: PMC4483587.
19. Topol A, Zhu S, Tran N, Simone A, Fang G, Brennand KJ. Altered WNT signaling in hiPSC NPCs derived from four schizophrenia patients. Biological psychiatry. 2015;78(6):e29-e34. doi: 10.1016/j.biopsych.2014.12.028. PubMed PMID: PMC4520784.
20. Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, et al. Increased abundance of translation machinery in stem cell–derived neural progenitor cells from four schizophrenia patients. Translational Psychiatry. 2015;5(10):e662. doi: 10.1038/tp.2015.118. PubMed PMID: PMC4930118.
21. Tong J, Xie J, Ren H, Liu J, Zhang W, Wei C, et al. Comparison of Glomerular Transcriptome Profiles of Adult-Onset Steroid Sensitive Focal Segmental Glomerulosclerosis and Minimal Change Disease. PLOS ONE. 2015;10(11):e0140453. doi: 10.1371/journal.pone.0140453.
22. Tomer Y, Dolan LM, Kahaly G, Divers J, D'Agostino RB, Jr., Imperatore G, et al. Genome wide identification of new genes and pathways in patients with both autoimmune thyroiditis and type 1 diabetes. Journal of autoimmunity. 2015;60:32-9. Epub 2015/04/27. doi: 10.1016/j.jaut.2015.03.006. PubMed PMID: 25936594.
23. Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, et al. Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in Glioblastoma stem-like cells. Cell reports. 2015;13(11):2425-39. doi: 10.1016/j.celrep.2015.11.021. PubMed PMID: PMC4691575.
24. The Genomes Project C. A global reference for human genetic variation. Nature. 2015;526:68. doi: 10.1038/nature15393
https://www.nature.com/articles/nature15393 - supplementary-information.
25. Teixeira A, Yen B, Gusella GL, Thomas AG, Mullen MP, Aberg J, et al. Prothymosin α Variants Isolated From CD8(+) T Cells and Cervicovaginal Fluid Suppress HIV-1 Replication Through Type I Interferon Induction. The Journal of Infectious Diseases. 2015;211(9):1467-75. doi: 10.1093/infdis/jiu643. PubMed PMID: PMC4425839.
26. Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, et al. ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior. Nat Med. 2015;21(10):1146-53. Epub 2015/09/22. doi: 10.1038/nm.3939. PubMed PMID: 26390241; PubMed Central PMCID: PMCPMC4598281.
27. Song W-M, Zhang B. Multiscale Embedded Gene Co-expression Network Analysis. PLOS Computational Biology. 2015;11(11):e1004574. doi: 10.1371/journal.pcbi.1004574.
28. Smith CC, Zhang C, Lin K, Lasater EA, Zhang Y, Massi E, et al. Characterizing and Overriding the Structural Mechanism of the Quizartinib-resistant FLT3 “Gatekeeper” F691L Mutation with PLX3397. Cancer discovery. 2015;5(6):668-79. doi: 10.1158/2159-8290.CD-15-0060. PubMed PMID: PMC4522415.
29. Simchoni N, Cunningham-Rundles C. TLR7- and TLR9-Responsive Human B Cells Share Phenotypic and Genetic Characteristics. The Journal of Immunology. 2015;194(7):3035. doi: 10.4049/jimmunol.1402690.
30. Sia D, Losic B, Moeini A, Cabellos L, Hao K, Revill K, et al. Massive parallel sequencing uncovers actionable FGFR2–PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. Nature Communications. 2015;6:6087. doi: 10.1038/ncomms7087
https://www.nature.com/articles/ncomms7087 - supplementary-information.
31. Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015;518(7538):187-96. doi: 10.1038/nature14132. PubMed PMID: 25673412.
32. Shen N, Clemente JC. Engineering the Microbiome: a Novel Approach to Immunotherapy for Allergic and Immune Diseases. Current Allergy and Asthma Reports. 2015;15(7):39. doi: 10.1007/s11882-015-0538-9.
33. Shen L. Automatic genome segmentation with HMM-ANN hybrid models. bioRxiv. 2015. doi: 10.1101/034579.
34. Shang Y, Filizola M. Opioid receptors: Structural and mechanistic insights into pharmacology and signaling. European journal of pharmacology. 2015;763(0 0):206-13. doi: 10.1016/j.ejphar.2015.05.012. PubMed PMID: PMC4584181.
35. Schneider S, Provasi D, Filizola M. The Dynamic Process of Drug-GPCR Binding at Either Orthosteric or Allosteric Sites Evaluated by Metadynamics. Methods in molecular biology (Clifton, NJ). 2015;1335:277-94. doi: 10.1007/978-1-4939-2914-6_18. PubMed PMID: PMC4703114.
36. Schliekelman MJ, Taguchi A, Zhu J, Dai X, Rodriguez J, Celiktas M, et al. Molecular portraits of epithelial, mesenchymal and hybrid states in lung adenocarcinoma and their relevance to survival. Cancer research. 2015;75(9):1789-800. doi: 10.1158/0008-5472.CAN-14-2535. PubMed PMID: PMC4846295.
37. Sanderson SC, Linderman MD, Zinberg R, Bashir A, Kasarskis A, Zweig M, et al. How do students react to analyzing their own genomes in a whole-genome sequencing course?: outcomes of a longitudinal cohort study. Genetics In Medicine. 2015;17:866. doi: 10.1038/gim.2014.203
https://www.nature.com/articles/gim2014203 - supplementary-information.
38. Sancho A, Li S, Paul T, Zhang F, Aguilo F, Vashisht A, et al. CHD6 regulates the topological arrangement of the CFTR locus. Human molecular genetics. 2015;24(10):2724-32. Epub 2015/01/28. doi: 10.1093/hmg/ddv032. PubMed PMID: 25631877.
39. Rivas MA, Pirinen M, Conrad DF, Lek M, Tsang EK, Karczewski KJ, et al. Impact of predicted protein-truncating genetic variants on the human transcriptome. Science (New York, NY). 2015;348(6235):666-9. doi: 10.1126/science.1261877. PubMed PMID: PMC4537935.
40. Ren C, Morohashi K, Plotnikov AN, Jakoncic J, Smith SG, Li J, et al. Small Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chemistry & biology. 2015;22(2):161-8. doi: 10.1016/j.chembiol.2014.11.021. PubMed PMID: PMC4336573.
41. Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, et al. Molecular systems evaluation of oligomerogenic APPE693Q and fibrillogenic APPKM670/671NL/PSEN1Δexon9 mouse models identifies shared features with human Alzheimer’s brain molecular pathology. Molecular Psychiatry. 2015;21:1099. doi: 10.1038/mp.2015.167
https://www.nature.com/articles/mp2015167 - supplementary-information.
42. Provasi D, Boz MB, Johnston JM, Filizola M. Preferred Supramolecular Organization and Dimer Interfaces of Opioid Receptors from Simulated Self-Association. PLOS Computational Biology. 2015;11(3):e1004148. doi: 10.1371/journal.pcbi.1004148.
43. Pierson E, the GC, Koller D, Battle A, Mostafavi S. Sharing and Specificity of Co-expression Networks across 35 Human Tissues. PLOS Computational Biology. 2015;11(5):e1004220. doi: 10.1371/journal.pcbi.1004220.
44. Petralia F, Wang P, Yang J, Tu Z. Integrative random forest for gene regulatory network inference. Bioinformatics. 2015;31(12):i197-i205. doi: 10.1093/bioinformatics/btv268. PubMed PMID: PMC4542785.
45. Pereira E, Camacho-Vanegas O, Anand S, Sebra R, Catalina Camacho S, Garnar-Wortzel L, et al. Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers. PLoS ONE. 2015;10(12):e0145754. doi: 10.1371/journal.pone.0145754. PubMed PMID: PMC4696808.
46. Pak TR, Kasarskis A. How Next-Generation Sequencing and Multiscale Data Analysis Will Transform Infectious Disease Management. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America. 2015;61(11):1695-702. doi: 10.1093/cid/civ670. PubMed PMID: PMC4643486.
47. Pak TR, Altman DR, Attie O, Sebra R, Hamula CL, Lewis M, et al. Whole-Genome Sequencing Identifies Emergence of a Quinolone Resistance Mutation in a Case of <span class="named-content genus-species" id="named-content-1">Stenotrophomonas maltophilia</span> Bacteremia. Antimicrobial Agents and Chemotherapy. 2015;59(11):7117. doi: 10.1128/AAC.01723-15.
48. Pak TR, Altman DR, Attie O, Sebra R, Hamula CL, Lewis M, et al. Whole-Genome Sequencing Identifies Emergence of a Quinolone Resistance Mutation in a Case of Stenotrophomonas maltophilia Bacteremia. Antimicrobial Agents and Chemotherapy. 2015;59(11):7117-20. doi: 10.1128/AAC.01723-15. PubMed PMID: PMC4604410.
49. Obregon-Tito AJ, Tito RY, Metcalf J, Sankaranarayanan K, Clemente JC, Ursell LK, et al. Subsistence strategies in traditional societies distinguish gut microbiomes. Nature Communications. 2015;6:6505. doi: 10.1038/ncomms7505
https://www.nature.com/articles/ncomms7505 - supplementary-information.
50. Nonnenmacher M, van Bakel H, Hajjar RJ, Weber T. High capsid-genome correlation facilitates creation of AAV libraries for directed evolution. Molecular therapy : the journal of the American Society of Gene Therapy. 2015;23(4):675-82. Epub 2015/02/10. doi: 10.1038/mt.2015.3. PubMed PMID: 25586687.
51. Nonnenmacher M, van Bakel H, Hajjar RJ, Weber T. High Capsid–Genome Correlation Facilitates Creation of AAV Libraries for Directed Evolution. Molecular Therapy. 2015;23(4):675-82. doi: 10.1038/mt.2015.3. PubMed PMID: PMC4395795.
52. Noh KM, Maze I, Zhao D, Xiang B, Wenderski W, Lewis PW, et al. ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons. Proc Natl Acad Sci U S A. 2015;112(22):6820-7. Epub 2014/12/30. doi: 10.1073/pnas.1411258112. PubMed PMID: 25538301; PubMed Central PMCID: PMCPMC4460490.
53. Nikpay M, Goel A, Won H-H, Hall LM, Willenborg C, Kanoni S, et al. A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nature genetics. 2015;47(10):1121-30. doi: 10.1038/ng.3396. PubMed PMID: PMC4589895.
54. Narzo AFD, Kozlenkov A, Ge Y, Zhang B, Sanelli L, May Z, et al. Decrease of mRNA Editing after Spinal Cord Injury is Caused by Down-regulation of ADAR2 that is Triggered by Inflammatory Response. Scientific Reports. 2015;5:12615. doi: 10.1038/srep12615. PubMed PMID: PMC4519770.
55. Mitsi V, Terzi D, Purushothaman I, Manouras L, Gaspari S, Neve RL, et al. RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states. Proc Natl Acad Sci U S A. 2015;112(36):E5088-97. Epub 2015/08/26. doi: 10.1073/pnas.1504283112. PubMed PMID: 26305935; PubMed Central PMCID: PMCPMC4568688.
56. Miltiadous O, Sia D, Hoshida Y, Fiel MI, Harrington AN, Thung SN, et al. Progenitor cell markers predict outcome of patients with hepatocellular carcinoma beyond Milan criteria undergoing liver transplantation. Journal of Hepatology. 2015;63(6):1368-77. doi: https://doi.org/10.1016/j.jhep.2015.07.025.
57. Miller MS, Rialdi A, Ho JSY, Tilove M, Martinez-Gil L, Moshkina NP, et al. Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis. Nature immunology. 2015;16(5):485-94. Epub 2015/03/30. doi: 10.1038/ni.3132. PubMed PMID: 25822250.
58. Mezei M. Use of circular variance to quantify the deviation of a macromolecule from the spherical shape. Journal of mathematical chemistry. 2015;53(10):2184-90. doi: 10.1007/s10910-015-0540-4. PubMed PMID: PMC4684833.
59. Mezei M. Statistical Properties of Protein-Protein Interfaces. Algorithms. 2015;8(2). doi: 10.3390/a8020092.
60. Menon MC, Chuang PY, Li Z, Wei C, Zhang W, Luan Y, et al. Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis. The Journal of Clinical Investigation. 2015;125(1):208-21. doi: 10.1172/JCI76902. PubMed PMID: PMC4382250.
61. Menon MC, Chuang PY, Li Z, Wei C, Zhang W, Luan Y, et al. Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis. The Journal of clinical investigation. 2015;125(1):208-21. Epub 2014/12/01. doi: 10.1172/JCI76902. PubMed PMID: 25437874.
62. Meng F, Speyer CL, Zhang B, Zhao Y, Chen W, Gorski DH, et al. PDGFRα and β Play Critical Roles in Mediating Foxq1-Driven Breast Cancer Stemness and Chemoresistance. Cancer research. 2015;75(3):584-93. doi: 10.1158/0008-5472.CAN-13-3029. PubMed PMID: PMC4384815.
63. Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, et al. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 2015;87(1):77-94. Epub 2015/07/04. doi: 10.1016/j.neuron.2015.06.014. PubMed PMID: 26139371; PubMed Central PMCID: PMCPMC4491146.
64. Mathers AJ, Stoesser N, Sheppard AE, Pankhurst L, Giess A, Yeh AJ, et al. Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae at a Single Institution: Insights into Endemicity from Whole-Genome Sequencing. Antimicrobial Agents and Chemotherapy. 2015;59(3):1656-63.
65. Ma M, Ru Y, Chuang L-S, Hsu N-Y, Shi L-S, Hakenberg J, et al. Disease-associated variants in different categories of disease located in distinct regulatory elements. BMC Genomics. 2015;16(Suppl 8):S3-S. doi: 10.1186/1471-2164-16-S8-S3. PubMed PMID: PMC4480828.
66. Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206. doi: 10.1038/nature14177. PubMed PMID: PMC4382211.
67. Liu J, Magri L, Zhang F, Marsh NO, Albrecht S, Huynh JL, et al. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015;35(1):352-65. doi: 10.1523/JNEUROSCI.2606-14.2015. PubMed PMID: 25568127.
68. Linderman MD, Bashir A, Diaz GA, Kasarskis A, Sanderson SC, Zinberg RE, et al. Preparing the next generation of genomicists: a laboratory-style course in medical genomics. BMC Medical Genomics. 2015;8(1):47. doi: 10.1186/s12920-015-0124-y.
69. Lin X, Zhao Y, Song W-m, Zhang B. Molecular classification and prediction in gastric cancer. Computational and Structural Biotechnology Journal. 2015;13:448-58. doi: 10.1016/j.csbj.2015.08.001. PubMed PMID: PMC4556804.
70. Li L, Cheng W-Y, Glicksberg BS, Gottesman O, Tamler R, Chen R, et al. Identification of type 2 diabetes subgroups through topological analysis of patient similarity. Science translational medicine. 2015;7(311):311ra174-311ra174. doi: 10.1126/scitranslmed.aaa9364. PubMed PMID: PMC4780757.
71. Latif R, Ali MR, Mezei M, Davies TF. Transmembrane Domains of Attraction on the TSH Receptor. Endocrinology. 2015;156(2):488-98. doi: 10.1210/en.2014-1509. PubMed PMID: PMC4298320.
72. Latif R, Ali MR, Ma R, David M, Morshed SA, Ohlmeyer M, et al. New Small Molecule Agonists to the Thyrotropin Receptor. Thyroid. 2015;25(1):51-62. doi: 10.1089/thy.2014.0119. PubMed PMID: PMC4291085.
73. Kwon Y-J, Petrie K, Leibovitch BA, Zeng L, Mezei M, Howell L, et al. Selective inhibition of SIN3 corepressor with avermectins as a novel therapeutic strategy in triple negative breast cancer. Molecular cancer therapeutics. 2015;14(8):1824-36. doi: 10.1158/1535-7163.MCT-14-0980-T. PubMed PMID: PMC4529816.
74. Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, et al. Integrative analysis of 111 reference human epigenomes. Nature. 2015;518(7539):317-30. Epub 2015/02/20. doi: 10.1038/nature14248. PubMed PMID: 25693563; PubMed Central PMCID: PMCPMC4530010.
75. Kocabayoglu P, Lade A, Lee YA, Dragomir A-C, Sun X, Fiel MI, et al. β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis. Journal of hepatology. 2015;63(1):141-7. Epub 2015/02/09. doi: 10.1016/j.jhep.2015.01.036. PubMed PMID: 25678385.
76. King LY, Canasto-Chibuque C, Johnson KB, Yip S, Chen X, Kojima K, et al. A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration. Gut. 2015;64(8):1296-302. Epub 2014/08/20. doi: 10.1136/gutjnl-2014-307862. PubMed PMID: 25143343.
77. Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 2015;523:459. doi: 10.1038/nature14618
https://www.nature.com/articles/nature14618 - supplementary-information.
78. Jiang P, Scarpa JR, Fitzpatrick K, Losic B, Gao VD, Hao K, et al. A systems approach identifies networks and genes linking sleep and stress: implications for neuropsychiatric disorders. Cell reports. 2015;11(5):835-48. Epub 2015/04/23. doi: 10.1016/j.celrep.2015.04.003. PubMed PMID: 25921536.
79. International G, Translational Research in Transplantation N. Design and Implementation of the International Genetics and Translational Research in Transplantation Network. Transplantation. 2015;99(11):2401-12. Epub 2015/11/04. doi: 10.1097/TP.0000000000000913. PubMed PMID: 26479416.
80. Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, et al. Integrative network analysis reveals molecular mechanisms of blood pressure regulation. Molecular Systems Biology. 2015;11(4):799. doi: 10.15252/msb.20145399. PubMed PMID: PMC4422556.
81. Hodes GE, Pfau ML, Purushothaman I, Ahn HF, Golden SA, Christoffel DJ, et al. Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress. The Journal of Neuroscience. 2015;35(50):16362-76. doi: 10.1523/jneurosci.1392-15.2015.
82. Hayes JE, Trynka G, Vijai J, Offit K, Raychaudhuri S, Klein RJ. Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements. PLOS ONE. 2015;10(9):e0139360. doi: 10.1371/journal.pone.0139360.
83. Hartmann BM, Thakar J, Albrecht RA, Avey S, Zaslavsky E, Marjanovic N, et al. Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses. Journal of Virology. 2015;89(20):10190-205. doi: 10.1128/JVI.01523-15. PubMed PMID: PMC4580178.
84. Hao K, Di Narzo AF, Ho L, Luo W, Li S, Chen R, et al. Shared genetic etiology underlying Alzheimer's disease and type 2 diabetes. Molecular Aspects of Medicine. 2015;43-44:66-76. doi: https://doi.org/10.1016/j.mam.2015.06.006.
85. Gymrek M, Willems T, Guilmatre A, Zeng H, Markus B, Georgiev S, et al. Abundant contribution of short tandem repeats to gene expression variation in humans. Nature Genetics. 2015;48:22. doi: 10.1038/ng.3461
https://www.nature.com/articles/ng.3461 - supplementary-information.
86. Glicksberg BS, Li L, Cheng W-Y, Shameer K, Hakenberg J, Castellanos R, et al. AN INTEGRATIVE PIPELINE FOR MULTI-MODAL DISCOVERY OF DISEASE RELATIONSHIPS. Pacific Symposium on Biocomputing Pacific Symposium on Biocomputing. 2015;20:407-18. PubMed PMID: PMC4345399.
87. Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, et al. Genetic fine-mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature genetics. 2015;47(12):1415-25. doi: 10.1038/ng.3437. PubMed PMID: PMC4666734.
88. Fulton BO, Sachs D, Beaty SM, Won ST, Lee B, Palese P, et al. Mutational analysis of measles virus suggests constraints on antigenic variation of the glycoproteins. Cell reports. 2015;11(9):1331-8. doi: 10.1016/j.celrep.2015.04.054. PubMed PMID: PMC4464907.
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