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2017 Published Papers

1. Zhao Y, Song W-M, Zhang F, Zhou M-M, Zhang W, Walsh MJ, et al. Distinct distributions of genomic features of the 5’ and 3’ partners of coding somatic cancer gene fusions: arising mechanisms and functional implications. Oncotarget. 2017;8(40):66769-83. doi: 10.18632/oncotarget.10734. PubMed PMID: PMC5620135.
2. Zhao W, Rasheed A, Tikkanen E, Lee J-J, Butterworth AS, Howson JMM, et al. Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. Nature Genetics. 2017;49:1450. doi: 10.1038/ng.3943 - supplementary-information.
3. Zhang Z, Hao K, Ross MJ, Murphy B, Menon MC. APOL1 G2 risk allele—clarifying nomenclature. Kidney International. 2017;92(2):518-9. doi:
4. Zhang P, Chu T, Dedousis N, Mantell BS, Sipula I, Li L, et al. DNA methylation alters transcriptional rates of differentially expressed genes and contributes to pathophysiology in mice fed a high fat diet. Molecular Metabolism. 2017;6(4):327-39. doi: 10.1016/j.molmet.2017.02.001. PubMed PMID: PMC5369282.
5. Zhang J, Peng S, Cheng H, Nomura Y, Di Narzo AF, Hao K. Genetic Pleiotropy between Nicotine Dependence and Respiratory Outcomes. Scientific Reports. 2017;7(1):16907. doi: 10.1038/s41598-017-16964-4.
6. Zhang H, Fillmore Brainson C, Koyama S, Redig AJ, Chen T, Li S, et al. Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2. Nature Communications. 2017;8:14922. doi: 10.1038/ncomms14922 - supplementary-information.
7. Zafar H, Shang Y, Li J, David GA, Fernandez JP, Molina H, et al. αIIbβ3 binding to a fibrinogen fragment lacking the γ-chain dodecapeptide is activation dependent and EDTA inducible. Blood Advances. 2017;1(7):417-28. doi: 10.1182/bloodadvances.2017004689. PubMed PMID: PMC5738983.
8. Yoo S, Wang W, Wang Q, Fiel MI, Lee E, Hiotis SP, et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Medicine. 2017;15(1):214. doi: 10.1186/s12916-017-0973-7.
9. Yano H, Provasi D, Cai NS, Filizola M, Ferré S, Javitch JA. Development of novel biosensors to study receptor-mediated activation of the G-protein α subunits Gs and Golf. Journal of Biological Chemistry. 2017;292(49):19989-98.
10. Yang Z, Jin M, Zhang Z, Lu J, Hao K. Classification Based on Feature Extraction For Hepatocellular Carcinoma Diagnosis Using High-throughput Dna Methylation Sequencing Data. Procedia Computer Science. 2017;107:412-7. doi:
11. Yang Y, Botton MR, Scott ER, Scott SA. Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing. Pharmacogenomics. 2017;18(7):673-85. doi: 10.2217/pgs-2017-0033.
12. Yang S, Hemarajata P, Hindler J, Li F, Adisetiyo H, Aldrovandi G, et al. Evolution and Transmission of Carbapenem-Resistant Klebsiella pneumoniae Expressing the blaOXA-232 Gene During an Institutional Outbreak Associated With Endoscopic Retrograde Cholangiopancreatography. Clinical Infectious Diseases. 2017;64(7):894-901. doi: 10.1093/cid/ciw876.
13. Yang J, Hagen J, Guntur KV, Allette K, Schuyler S, Ranjan J, et al. A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells. BMC Genomics. 2017;18:987. doi: 10.1186/s12864-017-4359-1. PubMed PMID: PMC5741891.
14. Yang B, Zhou W, Jiao J, Nielsen JB, Mathis MR, Heydarpour M, et al. Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve. Nature Communications. 2017;8:15481. doi: 10.1038/ncomms15481. PubMed PMID: PMC5458508.
15. Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, et al. A Comparison of mRNA Sequencing with Random Primed and 3′-Directed Libraries. Scientific Reports. 2017;7(1):14626. doi: 10.1038/s41598-017-14892-x.
16. Wheeler E, Leong A, Liu C-T, Hivert M-F, Strawbridge RJ, Podmore C, et al. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLOS Medicine. 2017;14(9):e1002383. doi: 10.1371/journal.pmed.1002383.
17. Wei C, Li L, Menon MC, Zhang W, Fu J, Kidd B, et al. Genomic Analysis of Kidney Allograft Injury Identifies Hematopoietic Cell Kinase as a Key Driver of Renal Fibrosis. Journal of the American Society of Nephrology. 2017;28(5):1385-93.
18. Webb TR, Erdmann J, Stirrups KE, Stitziel NO, Masca NGD, Jansen H, et al. Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. Journal of the American College of Cardiology. 2017;69(7):823-36. doi: 10.1016/j.jacc.2016.11.056. PubMed PMID: PMC5314135.
19. Webb BD, Metikala S, Wheeler PG, Sherpa MD, Houten SM, Horb ME, et al. Heterozygous Pathogenic Variant in DACT1 Causes an Autosomal-Dominant Syndrome with Features Overlapping Townes–Brocks Syndrome. Human mutation. 2017;38(4):373-7. doi: 10.1002/humu.23171. PubMed PMID: PMC5390682.
20. Watson CT, Cohain AT, Griffin RS, Chun Y, Grishin A, Hacyznska H, et al. Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions. Nature Communications. 2017;8(1):1943. doi: 10.1038/s41467-017-02188-7.
21. Watson C, Cohain A, Griffin R, Beckmann N, Grishin A, Haczynska H, et al. Analysis of Serial Peripheral Blood Transcriptomes from Peanut Allergic Children Undergoing Double-blind, Placebo-controlled Oral Food Challenges Reveals Key Drivers of the Acute Allergic Response to Peanut. Journal of Allergy and Clinical Immunology. 2017;139(2):AB189. doi: 10.1016/j.jaci.2016.12.615.
22. Wang H, Bender A, Wang P, Karakose E, Inabnet WB, Libutti SK, et al. Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas. Nature Communications. 2017;8:767. doi: 10.1038/s41467-017-00992-9. PubMed PMID: PMC5626682.
23. Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, et al. ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia. Nature. 2017;543(7644):265-9. Epub 2017/02/28. doi: 10.1038/nature21687. PubMed PMID: 28241141; PubMed Central PMCID: PMCPMC5372383.
24. Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, et al. <span hwp:id="article-title-1" class="article-title">Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney</span><span hwp:id="article-title-47" class="sub-article-title">Novelty and Significance</span&gt. Hypertension. 2017;70(3):e4.
25. Wain LV, Shrine N, Soler Artigas M, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, et al. Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature genetics. 2017;49(3):416-25. doi: 10.1038/ng.3787. PubMed PMID: PMC5326681.
26. Vatansever S, Gumus Z, Erman B. The Effects Of Oncogenic G12D Mutation On K-Ras Structure, Conformation And Dynamics. bioRxiv. 2017.
27. van Rooij FJA, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, et al. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. American Journal of Human Genetics. 2017;100(1):51-63. doi: 10.1016/j.ajhg.2016.11.016. PubMed PMID: PMC5223059.
28. Uzilov AV, Cheesman KC, Fink MY, Newman LC, Pandya C, Lalazar Y, et al. Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma. Cold Spring Harbor Molecular Case Studies. 2017;3(3):a001602. doi: 10.1101/mcs.a001602. PubMed PMID: PMC5411693.
29. Tsao AS, Wistuba I, Xia D, Byers L, Diao L, Wang J, et al. Germline and Somatic Smoothened Mutations in Non–Small-Cell Lung Cancer Are Potentially Responsive to Hedgehog Inhibitor Vismodegib. JCO Precision Oncology. 2017;1(1):1-10. doi: 10.1200/PO.17.00149.
30. Tosto G, Bird TD, Tsuang D, Bennett DA, Boeve BF, Cruchaga C, et al. Polygenic risk scores in familial Alzheimer disease. Neurology. 2017;88(12):1180.
31. Torrecilla S, Sia D, Harrington AN, Zhang Z, Cabellos L, Cornella H, et al. Trunk mutational events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma. Journal of Hepatology. 2017;67(6):1222-31. doi:
32. Tome-Garcia J, Tejero R, Nudelman G, Yong RL, Sebra R, Wang H, et al. Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR(+) Populations with Stem Cell Properties. Stem Cell Reports. 2017;8(5):1421-9. doi: 10.1016/j.stemcr.2017.03.019. PubMed PMID: PMC5425658.
33. Tcw J, Wang M, Pimenova AA, Bowles KR, Hartley BJ, Lacin E, et al. An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells. Stem Cell Reports. 2017;9(2):600-14. doi: 10.1016/j.stemcr.2017.06.018. PubMed PMID: PMC5550034.
34. Tamburini S, Clemente JC. Neonatal gut microbiota induces lung immunity against pneumonia. Nature Reviews Gastroenterology &Amp; Hepatology. 2017;14:263. doi: 10.1038/nrgastro.2017.34.
35. Stein L, Thaler A, Liang JW, Tuhrim S, Dhamoon AS, Dhamoon MS. Intermediate‐Term Risk of Stroke Following Cardiac Procedures in a Nationally Representative Data Set. Journal of the American Heart Association. 2017;6(12).
36. Shen L, Zhu J, Robert Li S-Y, Fan X. Detect differentially methylated regions using non-homogeneous hidden Markov model for methylation array data. Bioinformatics. 2017;33(23):3701-8. doi: 10.1093/bioinformatics/btx467.
37. Shen L. End-to-end Training for Whole Image Breast Cancer Diagnosis using An All Convolutional Design2017.
38. Sheen J-H, Strainic MG, Liu J, Zhang W, Yi Z, Medof ME, et al. TLR-Induced Murine Dendritic Cell (DC) Activation Requires DC-Intrinsic Complement. The Journal of Immunology. 2017;199(1):278.
39. Shameer K, Glicksberg BS, Hodos R, Johnson KW, Badgeley MA, Readhead B, et al. Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning. Briefings in Bioinformatics. 2017:bbw136-bbw. doi: 10.1093/bib/bbw136.
40. Segal LN, Clemente JC, Li Y, Ruan C, Cao J, Danckers M, et al. Anaerobic Bacterial Fermentation Products Increase Tuberculosis Risk in Antiretroviral-Drug-Treated HIV Patients. Cell Host & Microbe. 2017;21(4):530-7.e4. doi:
41. Scott SA, Owusu Obeng A, Botton MR, Yang Y, Scott ER, Ellis SB, et al. Institutional profile: translational pharmacogenomics at the Icahn School of Medicine at Mount Sinai. Pharmacogenomics. 2017;18(15):1381-6. doi: 10.2217/pgs-2017-0137.
42. Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. 2017;66(11):2888.
43. Sanderson SC, Linderman MD, Suckiel SA, Zinberg R, Wasserstein M, Kasarskis A, et al. Psychological and behavioural impact of returning personal results from whole-genome sequencing: the HealthSeq project. European Journal of Human Genetics. 2017;25(3):280-92. doi: 10.1038/ejhg.2016.178. PubMed PMID: PMC5315514.
44. Saccone NL, Emery LS, Sofer T, Gogarten SM, Becker DM, Bottinger EP, et al. Genome-Wide Association Study of Heavy Smoking and Daily/Nondaily Smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Nicotine & Tobacco Research. 2017:ntx107-ntx. doi: 10.1093/ntr/ntx107.
45. Romero Navarro JA, Phillips-Mora W, Arciniegas-Leal A, Mata-Quirós A, Haiminen N, Mustiga G, et al. Application of Genome Wide Association and Genomic Prediction for Improvement of Cacao Productivity and Resistance to Black and Frosty Pod Diseases. Frontiers in Plant Science. 2017;8:1905. doi: 10.3389/fpls.2017.01905. PubMed PMID: PMC5694496.
46. Ridge PG, Karch CM, Hsu S, Arano I, Teerlink CC, Ebbert MTW, et al. Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience. Genome Medicine. 2017;9(1):100. doi: 10.1186/s13073-017-0486-1.
47. Ribeiro EA, Scarpa JR, Garamszegi SP, Kasarskis A, Mash DC, Nestler EJ. Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder. Scientific Reports. 2017;7:5412. doi: 10.1038/s41598-017-05720-3. PubMed PMID: PMC5511210.
48. Rialdi A, Hultquist J, Jimenez-Morales D, Peralta Z, Campisi L, Fenouil R, et al. The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity. Cell. 2017;169(4):679-92.e14. doi:
49. Rengasamy M, Zhang F, Vashisht A, Song W-M, Aguilo F, Sun Y, et al. The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer. Nucleic Acids Research. 2017;45(19):11106-20. doi: 10.1093/nar/gkx727. PubMed PMID: PMC5737218.
50. Ramesh M, Hamm D, Simchoni N, Cunningham-Rundles C. Clonal and constricted T cell repertoire in Common Variable Immune Deficiency. Clinical immunology (Orlando, Fla). 2017;178:1-9. Epub 2015/01/14. doi: 10.1016/j.clim.2015.01.002. PubMed PMID: 25596453.
51. Rahman Adeeb H, Lavin Y, Kobayashi S, Leader A, Merad M. High‐dimensional single cell mapping of cerium distribution in the lung immune microenvironment of an active smoker. Cytometry Part B: Clinical Cytometry. 2017;0(0). doi: 10.1002/cyto.b.21545.
52. Qi H, Casalena G, Shi S, Yu L, Ebefors K, Sun Y, et al. Glomerular Endothelial Mitochondrial Dysfunction Is Essential and Characteristic of Diabetic Kidney Disease Susceptibility. Diabetes. 2017;66(3):763-78. doi: 10.2337/db16-0695. PubMed PMID: PMC5319717.
53. Polubriaginof F, Vanguri R, Quinnies K, Belbin G, Yahi A, Salmasian H, et al. Estimate of disease heritability using 7.4 million familial relationships inferred from electronic health records. bioRxiv. 2017.
54. Pollak J, Rai KG, Funk CC, Arora S, Lee E, Zhu J, et al. Ion channel expression patterns in glioblastoma stem cells with functional and therapeutic implications for malignancy. PLOS ONE. 2017;12(3):e0172884. doi: 10.1371/journal.pone.0172884.
55. Petralia F, Aushev VN, Gopalakrishnan K, Kappil M, W. Khin N, Chen J, et al. A new method to study the change of miRNA–mRNA interactions due to environmental exposures. Bioinformatics. 2017;33(14):i199-i207. doi: 10.1093/bioinformatics/btx256.
56. Peters LA, Perrigoue J, Mortha A, Iuga A, Song W-m, Neiman EM, et al. A functional genomics predictive network model identifies regulators of inflammatory bowel disease. Nature Genetics. 2017;49:1437. doi: 10.1038/ng.3947 - supplementary-information.
57. Peng S, Deyssenroth MA, Di Narzo AF, Lambertini L, Marsit CJ, Chen J, et al. Expression quantitative trait loci (eQTLs) in human placentas suggest developmental origins of complex diseases. Human Molecular Genetics. 2017;26(17):3432-41. doi: 10.1093/hmg/ddx265.
58. Pena CJ, Kronman HG, Walker DM, Cates HM, Bagot RC, Purushothaman I, et al. Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2. Science. 2017;356(6343):1185-8. Epub 2017/06/18. doi: 10.1126/science.aan4491. PubMed PMID: 28619944; PubMed Central PMCID: PMCPMC5539403.
59. Peña CJ, Kronman HG, Walker DM, Cates HM, Bagot RC, Purushothaman I, et al. Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2. Science. 2017;356(6343):1185.
60. Pappas K, Xu J, Zairis S, Resnick-Silverman L, Abate F, Steinbach N, et al. p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes. Molecular Cancer Research. 2017;15(8):1051.
61. Pandya C, Uzilov AV, Bellizzi J, Lau CY, Moe AS, Strahl M, et al. Genomic profiling reveals mutational landscape in parathyroid carcinomas. JCI Insight. 2017;2(6):e92061. doi: 10.1172/jci.insight.92061. PubMed PMID: PMC5358487.
62. Pandey G, Pandey OP, Rogers AJ, Hoffman GE, Raby BA, Weiss ST, et al. A Novel Nasal Brush-based Classifier of Asthma Identified by Machine Learning Analysis of Nasal RNA Sequence Data. bioRxiv. 2017.
63. Pak TR, Chacko KI, O’Donnell T, Huprikar SS, van Bakel H, Kasarskis A, et al. Estimating Local Costs Associated With Clostridium difficile Infection Using Machine Learning and Electronic Medical Records. Infection Control & Hospital Epidemiology. 2017;38(12):1478-86. Epub 2017/11/06. doi: 10.1017/ice.2017.214.
64. Ortiz-Virumbrales M, Moreno CL, Kruglikov I, Marazuela P, Sproul A, Jacob S, et al. CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2(N141I) neurons. Acta Neuropathologica Communications. 2017;5:77. doi: 10.1186/s40478-017-0475-z. PubMed PMID: PMC5660456.
65. O'Connell PJ, Zhang W, Ge Y, Menon MC, Murphy B. Biopsy transcriptome expression profiling: proper validation is key – Authors' reply. The Lancet. 2017;389(10069):601. doi:
66. Ng MCY, Graff M, Lu Y, Justice AE, Mudgal P, Liu C-T, et al. Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. PLOS Genetics. 2017;13(4):e1006719. doi: 10.1371/journal.pgen.1006719.
67. Nelson CP, Goel A, Butterworth AS, Kanoni S, Webb TR, Marouli E, et al. Association analyses based on false discovery rate implicate new loci for coronary artery disease. Nature Genetics. 2017;49:1385. doi: 10.1038/ng.3913 - supplementary-information.
68. Nadkarni GN, Galarneau G, Ellis SB, Nadukuru R, Zhang J, Scott SA, et al. Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans. Journal of the American College of Cardiology. 2017;69(12):1564-74. doi:
69. Moser DA, Doucet GE, Ing A, Dima D, Schumann G, Bilder RM, et al. An integrated brain–behavior model for working memory. Molecular Psychiatry. 2017. doi: 10.1038/mp.2017.247 - supplementary-information.
70. Monsell SE, Mock C, Fardo DW, Bertelsen S, Cairns NJ, Roe CM, et al. Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology. Alzheimer Disease & Associated Disorders. 2017;31(3).
71. Miller ML, Ren Y, Szutorisz H, Warren NA, Tessereau C, Egervári G, et al. Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. Molecular psychiatry. 2017:10.1038/mp.2017.80. doi: 10.1038/mp.2017.80. PubMed PMID: PMC5656565.
72. Mezei M. Using Force-Field Grids for Sampling Translation/Rotation of Partially Rigid Macromolecules. Algorithms. 2017;10(1). doi: 10.3390/a10010006.
73. Meyers JL, Zhang J, Wang JC, Su J, Kuo SI, Kapoor M, et al. An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry. Molecular Psychiatry. 2017;22:1767. doi: 10.1038/mp.2016.239 - supplementary-information.
74. McKenzie AT, Moyon S, Wang M, Katsyv I, Song W-M, Zhou X, et al. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease. Molecular Neurodegeneration. 2017;12(1):82. doi: 10.1186/s13024-017-0219-3.
75. Mayourian J, Cashman TJ, Ceholski DK, Johnson BV, Sachs D, Kaji DA, et al. <span hwp:id="article-title-1" class="article-title">Experimental and Computational Insight Into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity</span><span hwp:id="article-title-51" class="sub-article-title">Novelty and Significance</span&gt. Circulation Research. 2017;121(4):411.
76. Mathers AJ, Stoesser N, Chai W, Carroll J, Barry K, Cherunvanky A, et al. Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, blaKPC, in Klebsiella Species Is Elusive but Not Rare. Antimicrobial Agents and Chemotherapy. 2017;61(3).
77. Martín-Martínez M, Pérez-Gordillo FL, Álvarez de la Rosa D, Rodríguez Y, Gerona-Navarro G, González-Muñiz R, et al. Modulating Mineralocorticoid Receptor with Non-steroidal Antagonists. New Opportunities for the Development of Potent and Selective Ligands without Off-Target Side Effects. Journal of Medicinal Chemistry. 2017;60(7):2629-50. doi: 10.1021/acs.jmedchem.6b01065.
78. Martin AR, Gignoux CR, Walters RK, Wojcik GL, Neale BM, Gravel S, et al. Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations. American Journal of Human Genetics. 2017;100(4):635-49. doi: 10.1016/j.ajhg.2017.03.004. PubMed PMID: PMC5384097.
79. Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, et al. Rare and low-frequency coding variants alter human adult height. Nature. 2017;542:186. doi: 10.1038/nature21039 - supplementary-information.
80. Marino Kristen A, Shang Y, Filizola M. Insights into the function of opioid receptors from molecular dynamics simulations of available crystal structures. British Journal of Pharmacology. 2017;0(0). doi: 10.1111/bph.13774.
81. Marino KA, Shang Y, Filizola M. Insights into the function of opioid receptors from molecular dynamics simulations of available crystal structures. British Journal of Pharmacology. 2017:n/a-n/a. doi: 10.1111/bph.13774.
82. Macé A, Tuke MA, Deelen P, Kristiansson K, Mattsson H, Nõukas M, et al. CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nature Communications. 2017;8(1):744. doi: 10.1038/s41467-017-00556-x.
83. Loh YE, Koemeter-Cox A, Finelli MJ, Shen L, Friedel RH, Zou H. Comprehensive mapping of 5-hydroxymethylcytosine epigenetic dynamics in axon regeneration. Epigenetics. 2017;12(2):77-92. Epub 2016/12/06. doi: 10.1080/15592294.2016.1264560. PubMed PMID: 27918235; PubMed Central PMCID: PMCPMC5330438.
84. Loh YE, Feng J, Nestler E, Shen L. Bioinformatic Analysis for Profiling Drug-induced Chromatin Modification Landscapes in Mouse Brain Using ChlP-seq Data. Bio Protoc. 2017;7(3). Epub 2017/05/19. doi: 10.21769/BioProtoc.2123. PubMed PMID: 28516124; PubMed Central PMCID: PMCPMC5432020.
85. Llewellyn SR, Britton GJ, Contijoch EJ, Mortha A, Colombel J-F, Grinspan A, et al. Deciphering the combinatorial influence of diet and the microbiota on experimental colitis. bioRxiv. 2017.
86. Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, et al. Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics. 2017;49:1758. doi: 10.1038/ng.3977 - supplementary-information.
87. Lim ET, Uddin M, De Rubeis S, Chan Y, Kamumbu AS, Zhang X, et al. Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nature Neuroscience. 2017;20:1217. doi: 10.1038/nn.4598 - supplementary-information.
88. Liang J, Le TH, Edwards DRV, Tayo BO, Gaulton KJ, Smith JA, et al. Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. PLOS Genetics. 2017;13(5):e1006728. doi: 10.1371/journal.pgen.1006728.
89. Li YI, Wong G, Humphrey J, Raj T. Prioritizing Parkinson's Disease genes using population-scale transcriptomic data. bioRxiv. 2017:231001. doi: 10.1101/231001.
90. Li Y, Lucas-Osma AM, Black S, Bandet MV, Stephens MJ, Vavrek R, et al. Pericytes impair capillary blood flow and motor function after chronic spinal cord injury. Nature medicine. 2017;23(6):733-41. doi: 10.1038/nm.4331. PubMed PMID: PMC5716958.
91. Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, et al. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. Journal of the American Society of Nephrology : JASN. 2017;28(3):981-94. doi: 10.1681/ASN.2016020131. PubMed PMID: PMC5328154.
92. Li L, Greene I, Readhead B, Menon MC, Kidd BA, Uzilov AV, et al. Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach. Scientific Reports. 2017;7:39487. doi: 10.1038/srep39487. PubMed PMID: PMC5209709.
93. Li J, Rodriguez Y, Cheng C, Zeng L, Wong EYM, Xu CY, et al. EYA1's Conformation Specificity in Dephosphorylating Phosphothreonine in Myc and Its Activity on Myc Stabilization in Breast Cancer. Molecular and Cellular Biology. 2017;37(1):e00499-16. doi: 10.1128/MCB.00499-16. PubMed PMID: PMC5192086.
94. Li H, Cai J, Chen R, Zhao Z, Ying Z, Wang L, et al. Particulate Matter Exposure and Stress Hormone Levels. Circulation. 2017;136(7):618.
95. Levin MA, Joseph TT, Jeff JM, Nadukuru R, Ellis SB, Bottinger EP, et al. iGAS: A framework for using electronic intraoperative medical records for genomic discovery. Journal of Biomedical Informatics. 2017;67:80-9. doi:
96. Lee E, Pain M, Wang H, Herman JA, Toledo CM, DeLuca JG, et al. Sensitivity to <em>BUB1B</em> Inhibition Defines an Alternative Classification of Glioblastoma. Cancer Research. 2017;77(20):5518.
97. Lavin Y, Kobayashi S, Leader A, Amir E-aD, Elefant N, Bigenwald C, et al. Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses. Cell. 2017;169(4):750-65.e17. doi:
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